GJB3
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Beta-type (group I) subfamily. Note: This description may include information from UniProtKB.
|
Protein type: Channel, misc.; Membrane protein, integral; Membrane protein, multi-pass |
Chromosomal Location of mouse Ortholog: 4 D2.2|4 61.48 cM |
Cellular Component:
anchoring junction; cell junction; cell-cell junction; connexin complex; cytoplasm; gap junction; intracellular membrane-bounded organelle; membrane; plasma membrane
|
Molecular Function:
gap junction channel activity; protein binding
|
Biological Process:
cell communication; cell-cell signaling; placenta development
|
Reference #:
P28231
(UniProtKB)
|
Alt. Names/Synonyms: Cnx3; Cnx31; connexin 31; connexin c; Connexin-31; Cx31; CXB3; Cxn-31; Cxnc; D4Wsu144; D4Wsu144e; Gap junction beta-3 protein; gap junction membrane channel protein beta 3; gap junction protein, beta 3; Gjb-3; Gjb3; OTTMUSP00000009768; OTTMUSP00000009769
|
Gene Symbols: Gjb3
|
Molecular weight:
30,902 Da
|
Basal Isoelectric point:
9.08
Predict pI for various phosphorylation states
|