ATP1B2 This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth. Belongs to the X(+)/potassium ATPases subunit beta family. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component:  apical plasma membrane; cytoplasm; plasma membrane; sodium:potassium-exchanging ATPase complex
Molecular Function:  ATPase activator activity; ATPase binding; protein binding; sodium:potassium-exchanging ATPase activity
Biological Process:  cell adhesion; cell communication by electrical coupling involved in cardiac conduction; cellular potassium ion homeostasis; cellular sodium ion homeostasis; establishment or maintenance of transmembrane electrochemical gradient; ion transmembrane transport; leukocyte migration; membrane repolarization; positive regulation of ATPase activity; positive regulation of potassium ion import; positive regulation of potassium ion transmembrane transporter activity; positive regulation of sodium ion export across plasma membrane; potassium ion import across plasma membrane; protein stabilization; regulation of cardiac conduction; sodium ion export across plasma membrane
Reference #:  P14415 (UniProtKB)
Alt. Names/Synonyms: adhesion molecule on glia; AMOG; AT1B2; ATP1B2; ATPase, Na+/K+ transporting, beta 2 polypeptide; Na, K-ATPase beta-2 polypeptide; sodium/potassium-dependent ATPase beta-2 subunit; Sodium/potassium-dependent ATPase subunit beta-2; sodium/potassium-transporting ATPase beta-2 chain; Sodium/potassium-transporting ATPase subunit beta-2
Gene Symbols: ATP1B2
Molecular weight: 33,367 Da
Basal Isoelectric point: 8.57  Predict pI for various phosphorylation states
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ATP1B2

Protein Structure Not Found.

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