ANXA11 Binds specifically to calcyclin in a calcium-dependent manner. Required for midbody formation and completion of the terminal phase of cytokinesis. Belongs to the annexin family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Calcium-binding; Lipid-binding; Motility/polarity/chemotaxis; Nuclear envelope
Chromosomal Location of mouse Ortholog: 14 A3|14 15.06 cM
Cellular Component:  azurophil granule; cytoplasm; cytoskeleton; cytosol; midbody; nuclear envelope; nucleoplasm; nucleus; phagocytic vesicle; specific granule; spindle
Molecular Function:  calcium ion binding; calcium-dependent phospholipid binding; calcium-dependent protein binding; phosphatidylethanolamine binding; S100 protein binding
Biological Process:  cell cycle; cell division; cytokinetic process; phagocytosis; response to calcium ion
Reference #:  P97384 (UniProtKB)
Alt. Names/Synonyms: A830099O17Rik; Annexin A11; Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50); Annexin XI; Annexin-11; Anx; Anx11; Anxa11; Calcyclin-associated annexin 50; CAP-50; OTTMUSP00000021337
Gene Symbols: Anxa11
Molecular weight: 54,079 Da
Basal Isoelectric point: 7.53  Predict pI for various phosphorylation states
Select Structure to View Below

ANXA11

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein