dynactin 4 Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Belongs to the dynactin subunit 4 family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Microtubule-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 18|18 D3
Cellular Component:  centrosome; cytoplasm; cytoplasmic dynein complex; cytoskeleton; dynactin complex; kinetochore; spindle pole
Molecular Function:  protein N-terminus binding
Biological Process:  nuclear migration
Reference #:  Q8CBY8 (UniProtKB)
Alt. Names/Synonyms: 1110001K06Rik; 4930547K17Rik; C130039E17Rik; Dctn4; dynactin 4; Dynactin subunit 4; Dynactin subunit p62; p62
Gene Symbols: Dctn4
Molecular weight: 53,057 Da
Basal Isoelectric point: 7.84  Predict pI for various phosphorylation states
Select Structure to View Below

dynactin 4

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene