dynactin 4 Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Belongs to the dynactin subunit 4 family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Microtubule-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 5q33.1
Cellular Component:  cell cortex; centrosome; cytoplasm; cytosol; focal adhesion; kinetochore; nucleus; sarcomere; spindle pole; stress fiber
Molecular Function:  protein binding; protein N-terminus binding
Biological Process:  antigen processing and presentation of exogenous peptide antigen via MHC class II; ER to Golgi vesicle-mediated transport
Reference #:  Q9UJW0 (UniProtKB)
Alt. Names/Synonyms: DCTN4; dynactin 4 (p62); dynactin p62 subunit; Dynactin subunit 4; Dynactin subunit p62
Gene Symbols: DCTN4
Molecular weight: 52,337 Da
Basal Isoelectric point: 7.1  Predict pI for various phosphorylation states
Select Structure to View Below

dynactin 4

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein