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dynactin 4
Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Belongs to the dynactin subunit 4 family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Microtubule-binding; Motility/polarity/chemotaxis; Motor |
| Chromosomal Location of human Ortholog: 5q33.1 |
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Cellular Component:
cell cortex; centrosome; cytoplasm; cytoplasmic dynein complex; cytosol; dynactin complex; focal adhesion; kinetochore; nucleus; sarcomere; spindle pole; stress fiber
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Molecular Function:
protein binding
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Reference #:
Q9UJW0
(UniProtKB)
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Alt. Names/Synonyms: DCTN4; Dyn4; dynactin 4; dynactin 4 (p62); dynactin p62 subunit; Dynactin subunit 4; Dynactin subunit p62; P62
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Gene Symbols: DCTN4
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Molecular weight:
52,337 Da
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Basal Isoelectric point:
7.1
Predict pI for various phosphorylation states
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