GDAP1 Regulates the mitochondrial network by promoting mitochondrial fission. Belongs to the GST superfamily. Highly expressed in whole brain and spinal cord. Predominant expression in central tissues of the nervous system not only in neurons but also in Schwann cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1|1 A3
Cellular Component:  cytoplasm; cytosol; integral component of membrane; integral component of mitochondrial outer membrane; membrane; mitochondrial outer membrane; mitochondrion
Biological Process:  mitochondrial fission; mitochondrial fusion; mitochondrion organization; protein targeting to mitochondrion; response to retinoic acid
Reference #:  O88741 (UniProtKB)
Alt. Names/Synonyms: Ganglioside-induced differentiation-associated protein 1; ganglioside-induced differentiation-associated-protein 1; GDAP1; OTTMUSP00000025245
Gene Symbols: Gdap1
Molecular weight: 41,311 Da
Basal Isoelectric point: 8.51  Predict pI for various phosphorylation states
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GDAP1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene