GPX3
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. Belongs to the glutathione peroxidase family. Secreted in plasma. Note: This description may include information from UniProtKB.
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Protein type: EC 1.11.1.9; Lipid Metabolism - arachidonic acid; Other Amino Acids Metabolism - glutathione; Oxidoreductase; Secreted; Secreted, signal peptide |
Chromosomal Location of human Ortholog: 5q33.1 |
Cellular Component:
extracellular region; extracellular space
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Molecular Function:
glutathione peroxidase activity; identical protein binding; protein binding; selenium binding
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Biological Process:
cellular oxidant detoxification; hydrogen peroxide catabolic process; response to lipid hydroperoxide
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Reference #:
P22352
(UniProtKB)
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Alt. Names/Synonyms: Extracellular glutathione peroxidase; Glutathione peroxidase 3; glutathione peroxidase 3 (plasma); GPx-3; GPx-P; GPX3; GPXP; GSHPx-3; GSHPx-P; Plasma glutathione peroxidase; selenoprotein GPX3
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Gene Symbols: GPX3
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Molecular weight:
25,552 Da
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Basal Isoelectric point:
8.26
Predict pI for various phosphorylation states
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