EM55 Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity. Belongs to the MAGUK family. Ubiquitous. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Kinase, other
Chromosomal Location of mouse Ortholog: X A7.3|X 38.15 cM
Cellular Component:  cell projection; cortical cytoskeleton; cytosol; membrane; nuclear speck; plasma membrane
Molecular Function:  protein binding
Biological Process:  regulation of neutrophil chemotaxis
Reference #:  P70290 (UniProtKB)
Alt. Names/Synonyms: 55 kDa erythrocyte membrane protein; 55kD; 55kDa; C130070C03Rik; EM55; erythrocyte protein p55; membrane protein, palmitoylated; Membrane protein, palmitoylated 1; Mpp1; OTTMUSP00000022728; p55
Gene Symbols: Mpp1
Molecular weight: 52,227 Da
Basal Isoelectric point: 6.72  Predict pI for various phosphorylation states
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EM55

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene