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HAO2
Catalyzes the oxidation of L-alpha-hydroxy acids as well as, more slowly, that of L-alpha-amino acids. Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 1.1.3.15; Oxidoreductase |
| Chromosomal Location of Human Ortholog: 3 F2.2|3 42.9 cM |
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Cellular Component:
peroxisome
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Molecular Function:
(S)-2-hydroxy-acid oxidase activity; catalytic activity; FMN binding; long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity; medium-chain-(S)-2-hydroxy-acid oxidase activity; oxidoreductase activity; signaling receptor binding; very-long-chain-(S)-2-hydroxy-acid oxidase activity
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Biological Process:
fatty acid oxidation; mandelate metabolic process; oxidation-reduction process; protein homooligomerization
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Reference #:
Q9NYQ2
(UniProtKB)
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Alt. Names/Synonyms: (S)-2-hydroxy-acid oxidase, peroxisomal; AI325478; Hao-2; Hao2; Hao3; HAOX2; Haox3; hydroxyacid oxidase (glycolate oxidase) 3; Hydroxyacid oxidase 2; hydroxyacid oxidase 2, kidney; Medium chain alpha-hydroxy acid oxidase; medium-chain 2-hydroxy acid oxidase HAOX3; Medium-chain L-2-hydroxy acid oxidase; OTTMUSP00000007242
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Gene Symbols: Hao2
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Molecular weight:
38,700 Da
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Basal Isoelectric point:
7.55
Predict pI for various phosphorylation states
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