HAO2 Catalyzes the oxidation of L-alpha-hydroxy acids as well as, more slowly, that of L-alpha-amino acids. Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC; Oxidoreductase
Chromosomal Location of Human Ortholog: 3 F2.2|3 42.9 cM
Cellular Component:  peroxisome
Molecular Function:  (S)-2-hydroxy-acid oxidase activity; catalytic activity; FMN binding; long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity; medium-chain-(S)-2-hydroxy-acid oxidase activity; oxidoreductase activity; signaling receptor binding; very-long-chain-(S)-2-hydroxy-acid oxidase activity
Biological Process:  fatty acid oxidation; mandelate metabolic process; oxidation-reduction process; protein homooligomerization
Reference #:  Q9NYQ2 (UniProtKB)
Alt. Names/Synonyms: (S)-2-hydroxy-acid oxidase, peroxisomal; AI325478; Hao-2; Hao2; Hao3; HAOX2; Haox3; hydroxyacid oxidase (glycolate oxidase) 3; Hydroxyacid oxidase 2; hydroxyacid oxidase 2, kidney; Medium chain alpha-hydroxy acid oxidase; medium-chain 2-hydroxy acid oxidase HAOX3; Medium-chain L-2-hydroxy acid oxidase; OTTMUSP00000007242
Gene Symbols: Hao2
Molecular weight: 38,700 Da
Basal Isoelectric point: 7.55  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene