PDE7B Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain. Belongs to the cyclic nucleotide phosphodiesterase family. PDE7 subfamily. Highly expressed in brain. Also expressed in heart, liver, skeletal muscle and pancreas. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.4.53; Nucleotide Metabolism - purine; Phosphodiesterase
Chromosomal Location of mouse Ortholog: 10|10 A3
Cellular Component: 
Molecular Function:  3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; hydrolase activity; metal ion binding; phosphoric diester hydrolase activity
Biological Process:  signal transduction
Reference #:  Q9QXQ1 (UniProtKB)
Alt. Names/Synonyms: cAMP-specific 3',5'-cyclic phosphodiesterase 7B; Pde7b; phosphodiesterase 7B
Gene Symbols: Pde7b
Molecular weight: 51,337 Da
Basal Isoelectric point: 6.97  Predict pI for various phosphorylation states
Select Structure to View Below

PDE7B

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene