USP40 May be catalytically inactive. Belongs to the peptidase C19 family. Broadly expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; EC; Hydrolase; Ubiquitin-specific protease
Chromosomal Location of mouse Ortholog: 1|1 D
Cellular Component:  cytosol
Molecular Function:  cysteine-type endopeptidase activity; cysteine-type peptidase activity; hydrolase activity; peptidase activity; thiol-dependent ubiquitin-specific protease activity; thiol-dependent ubiquitinyl hydrolase activity
Biological Process:  protein deubiquitination; proteolysis; regulation of protein stability; ubiquitin-dependent protein catabolic process
Reference #:  Q8BWR4 (UniProtKB)
Alt. Names/Synonyms: B230215L03Rik; C730029K03; Deubiquitinating enzyme 40; Ubiquitin carboxyl-terminal hydrolase 40; ubiquitin specific peptidase 40; ubiquitin specific protease 40; Ubiquitin thioesterase 40; ubiquitin thiolesterase 40; Ubiquitin-specific-processing protease 40; UBP40; Usp40
Gene Symbols: Usp40
Molecular weight: 139,952 Da
Basal Isoelectric point: 5.42  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene