USP40 May be catalytically inactive. Belongs to the peptidase C19 family. Broadly expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; EC; Hydrolase; Ubiquitin-specific protease
Chromosomal Location of human Ortholog: 2q37.1
Cellular Component:  cytosol; nucleus
Molecular Function:  cysteine-type deubiquitinase activity; cysteine-type endopeptidase activity
Biological Process:  protein deubiquitination; regulation of protein stability; ubiquitin-dependent protein catabolic process
Reference #:  Q9NVE5 (UniProtKB)
Alt. Names/Synonyms: Deubiquitinating enzyme 40; FLJ10785; FLJ42100; Ubiquitin carboxyl-terminal hydrolase 40; ubiquitin specific peptidase 40; ubiquitin specific protease 40; Ubiquitin thioesterase 40; ubiquitin thiolesterase 40; Ubiquitin-specific-processing protease 40; UBP40; USP40
Gene Symbols: USP40
Molecular weight: 140,130 Da
Basal Isoelectric point: 5.46  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene