Helios
Associates with Ikaros at centromeric heterochromatin. Belongs to the Ikaros C2H2-type zinc-finger protein family. 8 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: C2H2-type zinc finger protein; Transcription factor |
Chromosomal Location of mouse Ortholog: 1|1 C3 |
Cellular Component:
nucleus
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Molecular Function:
DNA binding; DNA-binding transcription factor activity; identical protein binding; metal ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding
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Biological Process:
positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II
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Reference #:
P81183
(UniProtKB)
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Alt. Names/Synonyms: A730095J18Rik; Helios; IKAROS family zinc finger 2; Ikaros family zinc finger protein 2; Ikzf2; Zfpn; Zfpn1a2; Zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); Znfn1a2
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Gene Symbols: Ikzf2
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Molecular weight:
59,401 Da
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Basal Isoelectric point:
6.21
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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