Helios Associates with Ikaros at centromeric heterochromatin. Belongs to the Ikaros C2H2-type zinc-finger protein family. 8 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; Transcription factor
Chromosomal Location of Human Ortholog: 1|1 C3
Cellular Component:  nucleoplasm; nucleus
Molecular Function:  DNA binding; DNA-binding transcription factor activity; metal ion binding; nucleic acid binding; protein heterodimerization activity; protein homodimerization activity; transcription regulatory region DNA binding
Biological Process:  positive regulation of transcription by RNA polymerase II
Reference #:  P81183 (UniProtKB)
Alt. Names/Synonyms: A730095J18Rik; Helios; IKAROS family zinc finger 2; Ikaros family zinc finger protein 2; Ikzf2; Zfpn; Zfpn1a2; Zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); Znfn1a2
Gene Symbols: Ikzf2
Molecular weight: 59,401 Da
Basal Isoelectric point: 6.21  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Helios

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene