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GCP3
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Belongs to the TUBGCP family. Ubiquitously expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cytoskeletal; Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 8|8 A1.1 |
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Cellular Component:
centriole; centrosome; cytoplasm; cytoskeleton; equatorial microtubule organizing center; gamma-tubulin complex; microtubule; microtubule organizing center; polar microtubule; spindle pole
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Molecular Function:
gamma-tubulin binding; microtubule minus-end binding
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Biological Process:
cytoplasmic microtubule organization; meiotic cell cycle; microtubule cytoskeleton organization; microtubule nucleation; mitotic cell cycle; spindle assembly
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Reference #:
P58854
(UniProtKB)
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Alt. Names/Synonyms: Gamma-tubulin complex component 3; GCP; GCP-3; Gcp3; Spc; Spc98p; spindle pole body protein; Tubgcp3; tubulin, gamma complex associated protein 3
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Gene Symbols: Tubgcp3
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Molecular weight:
103,469 Da
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Basal Isoelectric point:
8.56
Predict pI for various phosphorylation states
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