GCP3 Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Belongs to the TUBGCP family. Ubiquitously expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of mouse Ortholog: 8|8 A1.1
Cellular Component:  centriole; centrosome; cytoplasm; cytoskeleton; equatorial microtubule organizing center; gamma-tubulin complex; microtubule; microtubule organizing center; polar microtubule; spindle pole
Molecular Function:  gamma-tubulin binding; microtubule minus-end binding
Biological Process:  cytoplasmic microtubule organization; meiotic cell cycle; microtubule cytoskeleton organization; microtubule nucleation; mitotic cell cycle; spindle assembly
Reference #:  P58854 (UniProtKB)
Alt. Names/Synonyms: Gamma-tubulin complex component 3; GCP; GCP-3; Gcp3; Spc; Spc98p; spindle pole body protein; Tubgcp3; tubulin, gamma complex associated protein 3
Gene Symbols: Tubgcp3
Molecular weight: 103,469 Da
Basal Isoelectric point: 8.56  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein