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GCP3
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Belongs to the TUBGCP family. Ubiquitously expressed. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cytoskeletal; Motility/polarity/chemotaxis |
| Chromosomal Location of human Ortholog: 13q34 |
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Cellular Component:
centriole; centrosome; cytoplasm; cytosol; equatorial microtubule organizing center; gamma-tubulin complex; polar microtubule; spindle
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Molecular Function:
gamma-tubulin binding; microtubule minus-end binding; protein binding; structural constituent of cytoskeleton; structural molecule activity
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Biological Process:
cytoplasmic microtubule organization; meiotic cell cycle; microtubule nucleation; mitotic cell cycle; single fertilization; spindle assembly
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Reference #:
Q96CW5
(UniProtKB)
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Alt. Names/Synonyms: 104p; ALP6; Gamma-ring complex protein 104 kDa; Gamma-tubulin complex component 3; GCP-3; GCP3; Grip104; h104p; hGCP3; hGrip104; hSpc98; SPBC98; Spc98; Spc98p; Spindle pole body protein Spc98 homolog; TUBGCP3; tubulin gamma complex associated protein 3; tubulin, gamma complex associated protein 3
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Gene Symbols: TUBGCP3
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Molecular weight:
103,571 Da
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Basal Isoelectric point:
8.35
Predict pI for various phosphorylation states
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