Lmr2 Phosphorylates PPP1C, phosphorylase b and CFTR. Belongs to the protein kinase superfamily. Tyr protein kinase family. Mainly expressed in skeletal muscle, and weakly in brain and pancreas. Note: This description may include information from UniProtKB.
Protein type: EC; Kinase, protein; Lmr family; Membrane protein, integral; Membrane protein, multi-pass; Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group
Chromosomal Location of Human Ortholog: 5|5 G2
Cellular Component:  cytoplasm; early endosome; Golgi apparatus; growth cone; integral component of membrane; integral component of plasma membrane; membrane; neuronal cell body; perinuclear region of cytoplasm; receptor complex; recycling endosome
Molecular Function:  ATP binding; kinase activity; myosin VI binding; nucleotide binding; protein kinase activity; protein phosphatase inhibitor activity; protein serine/threonine kinase activity; transferase activity; transmembrane receptor protein tyrosine kinase activity
Biological Process:  axon guidance; early endosome to late endosome transport; endocytic recycling; nervous system development; neurotrophin TRK receptor signaling pathway; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; phosphorylation; protein autophosphorylation; protein phosphorylation; receptor recycling; transferrin transport; transmembrane receptor protein tyrosine kinase signaling pathway
Reference #:  Q3TYD6 (UniProtKB)
Alt. Names/Synonyms: 2900041G10Rik; A330101P12Rik; aatyk2; apoptosis-associated tyrosine kinase 2; Brain-enriched kinase; Brek; cprk; Kiaa1079; KPI-2; KPI2; Lemur tyrosine kinase 2; Lmtk2; Serine/threonine-protein kinase LMTK2
Gene Symbols: Lmtk2
Molecular weight: 160,508 Da
Basal Isoelectric point: 4.37  Predict pI for various phosphorylation states
CST Pathways:  Tyrosine Kinases & Substrates
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene