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CapZIP
Stress-induced phosphorylation of CAPZIP may regulate the ability of F-actin-capping protein to remodel actin filament assembly. Highly expressed in skeletal muscle and more weakly in cardiac muscle. Also expressed in several lymphoid organs, including spleen, thymus, peripheral blood leukocytes, lymph node and bone marrow. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Cytoskeletal |
| Chromosomal Location of human Ortholog: 1q24.2 |
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Cellular Component:
actin filament; cytosol; early endosome; WASH complex
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Molecular Function:
actin filament binding; phosphatidylinositol phosphate binding; retromer complex binding
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Biological Process:
cellular hyperosmotic response; protein localization to endosome; retrograde transport, endosome to Golgi; skeletal muscle contraction
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Reference #:
Q6JBY9
(UniProtKB)
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Alt. Names/Synonyms: CapZ-interacting protein; CAPZIP; CPZIP; MGC126585; MGC126611; MGC21854; MK2S4; Protein kinase substrate CapZIP; protein kinase substrate MK2S4; RCSD domain containing 1; RCSD domain-containing protein 1; RCSD1
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Gene Symbols: RCSD1
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Molecular weight:
44,504 Da
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Basal Isoelectric point:
5.34
Predict pI for various phosphorylation states
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