SSTR3 Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. Brain, pituitary and pancreas. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 22q13.1
Cellular Component:  ciliary membrane; cilium; cytoplasm; non-motile cilium; plasma membrane
Molecular Function:  protein binding; signaling receptor binding; somatostatin receptor activity
Biological Process:  cell-cell signaling; cellular response to estradiol stimulus; cellular response to glucocorticoid stimulus; cerebellum development; forebrain development; G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; hormone-mediated apoptotic signaling pathway; negative regulation of cell proliferation; response to starvation; somatostatin signaling pathway; spermatogenesis
Reference #:  P32745 (UniProtKB)
Alt. Names/Synonyms: somatostatin receptor 3; Somatostatin receptor type 3; SS-3-R; SS3-R; SS3R; SSR-28; SSR3; SSTR3
Gene Symbols: SSTR3
Molecular weight: 45,847 Da
Basal Isoelectric point: 8.91  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB