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SSTR3
Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. Brain, pituitary and pancreas. Note: This description may include information from UniProtKB.
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| Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR |
| Chromosomal Location of Human Ortholog: 22q13.1 |
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Cellular Component:
ciliary membrane; cilium; cytoplasm; non-motile cilium; plasma membrane
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Molecular Function:
protein binding; signaling receptor binding; somatostatin receptor activity
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Biological Process:
cell-cell signaling; cellular response to estradiol stimulus; cellular response to glucocorticoid stimulus; cerebellum development; forebrain development; G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; hormone-mediated apoptotic signaling pathway; negative regulation of cell proliferation; response to starvation; somatostatin signaling pathway; spermatogenesis
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Reference #:
P32745
(UniProtKB)
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Alt. Names/Synonyms: somatostatin receptor 3; Somatostatin receptor type 3; SS-3-R; SS3-R; SS3R; SSR-28; SSR3; SSTR3
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Gene Symbols: SSTR3
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Molecular weight:
45,847 Da
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Basal Isoelectric point:
8.91
Predict pI for various phosphorylation states
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