IRTKS May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Cytoskeletal
Chromosomal Location of Human Ortholog: 7q21.3-q22.1
Cellular Component:  cytosol; nucleoplasm; plasma membrane
Molecular Function:  actin binding; proline-rich region binding; protein binding
Biological Process:  cell-cell adhesion; plasma membrane organization; positive regulation of actin cytoskeleton reorganization; positive regulation of actin filament polymerization; regulation of insulin receptor signaling pathway; response to bacterium
Reference #:  Q9UHR4 (UniProtKB)
Alt. Names/Synonyms: BAI1-associated protein 2-like 1; BAI1-associated protein 2-like protein 1; BAIAP2L1; BI2L1; Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; FLJ42275; Insulin receptor tyrosine kinase substrate; IRTKS
Gene Symbols: BAIAP2L1
Molecular weight: 56,883 Da
Basal Isoelectric point: 8.82  Predict pI for various phosphorylation states
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IRTKS

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene