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TOM1
May be involved in intracellular trafficking. Probable association with membranes. Belongs to the TOM1 family. Widely expressed. Highly expressed in skeletal muscle, heart, placenta and liver. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of mouse Ortholog: 8|8 C1 |
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Cellular Component:
cytoplasm; cytosol; early endosome; endosome; endosome membrane; membrane
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Molecular Function:
clathrin binding; clathrin heavy chain binding; myosin VI binding; phosphatidylinositol binding; phosphatidylinositol-5-phosphate binding; polyubiquitin modification-dependent protein binding; protein binding; ubiquitin binding
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Biological Process:
autophagosome-lysosome fusion; endosomal transport; positive regulation of autophagosome maturation; protein transport; regulation of endosome organization; signal transduction; substrate localization to autophagosome
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Reference #:
O88746
(UniProtKB)
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Alt. Names/Synonyms: Target of Myb protein 1; target of myb1 homolog; target of myb1 homolog (chicken); Target of Myb1 membrane trafficking protein; target of myb1 trafficking protein; Tom1
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Gene Symbols: Tom1
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Molecular weight:
54,325 Da
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Basal Isoelectric point:
4.83
Predict pI for various phosphorylation states
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