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S100A10
Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase. Belongs to the S-100 family. Note: This description may include information from UniProtKB.
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| Protein type: Calcium-binding |
| Chromosomal Location of human Ortholog: 1q21.3 |
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Cellular Component:
AnxA2-p11 complex; cell surface; cytoplasm; extracellular space; membrane raft; nuclear matrix; plasma membrane protein complex; RNA polymerase II transcription regulator complex
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Molecular Function:
calcium ion binding; calcium-dependent protein binding; lipid binding; protein binding; protein homodimerization activity; transmembrane transporter binding
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Biological Process:
membrane raft assembly; mRNA transcription by RNA polymerase II; positive regulation of binding; positive regulation of exocytosis; positive regulation of focal adhesion assembly; positive regulation of GTPase activity; positive regulation of plasma membrane repair; positive regulation of plasminogen activation; positive regulation of stress fiber assembly; positive regulation of substrate adhesion-dependent cell spreading; positive regulation of transcription by RNA polymerase II; protein localization to plasma membrane; regulation of neurogenesis; vesicle budding from membrane
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Reference #:
P60903
(UniProtKB)
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Alt. Names/Synonyms: 42C; annexin II ligand, calpactin I, light polypeptide; annexin II tetramer (AIIt) p11 subunit; ANX2L; ANX2LG; Ca[1]; CAL1L; Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; CLP11; GP11; MGC111133; p10; p10 protein; p11; Protein S100-A10; S100 calcium binding protein A10; S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100 calcium-binding protein A10; S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11)); S100A10; S10AA
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Gene Symbols: S100A10
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Molecular weight:
11,203 Da
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Basal Isoelectric point:
6.82
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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