C3orf33 Isoform 2: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane. Highly expressed in ileocecal tissue and endometrium. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of human Ortholog: 3q25.31
Cellular Component:  extracellular space; membrane
Molecular Function:  protein binding
Biological Process:  negative regulation of ERK1 and ERK2 cascade; regulation of DNA-binding transcription factor activity
Reference #:  Q6P1S2 (UniProtKB)
Alt. Names/Synonyms: AC3-33; AP-1 activity suppressor; C3orf33; CC033; chromosome 3 open reading frame 33; FLJ31139; hypothetical protein LOC285315; Protein AC3-33; Protein C3orf33; Uncharacterized protein C3orf33
Gene Symbols: C3orf33
Molecular weight: 33,765 Da
Basal Isoelectric point: 9.85  Predict pI for various phosphorylation states
Select Structure to View Below

C3orf33

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene