DLG7 Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. Belongs to the SAPAP family. Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; Microtubule-binding
Chromosomal Location of Human Ortholog: 14 C1|14 24.6 cM
Cellular Component:  cytoplasm; cytoskeleton; cytosol; microtubule organizing center; mitochondrion; nucleus; spindle pole centrosome
Molecular Function:  phosphoprotein phosphatase activity
Biological Process:  cell cycle; signaling
Reference #:  Q8K4R9 (UniProtKB)
Alt. Names/Synonyms: C77459; C86398; DAP-5; Discs large homolog 7; discs, large (Drosophila) homolog-associated protein 5; discs, large homolog 7; discs, large homolog-associated protein 5; Disks large-associated protein 5; Disks large-associated protein DLG7; Dlg; DLG associated protein 5; Dlg7; Dlgap5; DLGP5; Hepatoma up-regulated protein homolog; HURP; Kiaa0008; mKIAA0008
Gene Symbols: Dlgap5
Molecular weight: 90,196 Da
Basal Isoelectric point: 9.28  Predict pI for various phosphorylation states
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DLG7

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene