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DPP8
Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. Belongs to the peptidase S9B family. DPPIV subfamily. Ubiquitously expressed, with highest levels in testis, placenta, prostate, muscle and brain. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.4.14.5; Protease |
| Chromosomal Location of mouse Ortholog: 9|9 C |
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Cellular Component:
cytoplasm; cytosol
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Molecular Function:
aminopeptidase activity; dipeptidyl-peptidase activity; hydrolase activity; peptidase activity; serine-type peptidase activity
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Biological Process:
negative regulation of programmed cell death; proteolysis
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Reference #:
Q80YA7
(UniProtKB)
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Alt. Names/Synonyms: 2310004I03Rik; 4932434F09Rik; AI666706; Dipeptidyl peptidase 8; Dipeptidyl peptidase VIII; dipeptidylpeptidase 8; DP8; DPP VIII; Dpp8
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Gene Symbols: Dpp8
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Molecular weight:
102,186 Da
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Basal Isoelectric point:
5.51
Predict pI for various phosphorylation states
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