MAFA Transcription factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1. Binds the insulin enhancer C1/RIPE3b element. Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence. Belongs to the bZIP family. Maf subfamily. Expressed in the islets of Langerhans (at protein level). Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Oncoprotein; Transcription factor; Tumor suppressor
Cellular Component: 
Reference #:  O57342 (UniProtKB)
Alt. Names/Synonyms: BZip transcription factor MafA; MAFA; Transcription factor MafA
Gene Symbols: MAFA
Molecular weight: 32,464 Da
Basal Isoelectric point: 7.38  Predict pI for various phosphorylation states
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MAFA

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB