NEK4 a protein kinase of the NEK family. Highly conserved between the mouse and human and expressed at high levels in the testis. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.11.1; Kinase, protein; NEK family; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component:  ciliary rootlet; cytoplasm; cytosol
Molecular Function:  ATP binding; manganese ion binding; protein binding; protein serine/threonine kinase activity
Biological Process:  activation of protein kinase activity; cell division; cellular response to DNA damage stimulus; mitotic cell cycle; positive regulation of transcription, DNA-templated; protein amino acid phosphorylation; regulation of cellular senescence; regulation of mitotic cell cycle; regulation of replicative cell aging; regulation of response to DNA damage stimulus
Reference #:  P51957 (UniProtKB)
Alt. Names/Synonyms: MGC33171; NEK4; Never in mitosis A-related kinase 4; NIMA (never in mitosis gene a)-related kinase 4; NimA-related protein kinase 4; NRK2; pp12301; serine/threonine kinase 2; serine/threonine protein kinase-2; Serine/threonine-protein kinase 2; Serine/threonine-protein kinase Nek4; Serine/threonine-protein kinase NRK2; STK2
Gene Symbols: NEK4
Molecular weight: 94,597 Da
Basal Isoelectric point: 8.04  Predict pI for various phosphorylation states
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NEK4

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein