GPIbB Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium. Expressed in heart and brain. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell surface; Membrane protein, integral
Chromosomal Location of Human Ortholog: 16 A3|16 11.53 cM
Cellular Component:  integral component of membrane; integral component of plasma membrane; membrane
Molecular Function:  identical protein binding
Biological Process:  blood coagulation; cell adhesion; hemostasis
Reference #:  P56400 (UniProtKB)
Alt. Names/Synonyms: CD42c; glycoprotein Ib, beta polypeptide; GP-Ib beta; Gp1bb; GPIb-beta; GPIbB; Platelet glycoprotein Ib beta chain
Gene Symbols: Gp1bb
Molecular weight: 21,763 Da
Basal Isoelectric point: 10.51  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene