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DRAK2
Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney. Note: This description may include information from UniProtKB.
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| Protein type: CAMK group; DAPK family; DAPK subfamily; EC 2.7.11.1; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor) |
| Chromosomal Location of human Ortholog: 2q32.3 |
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Cellular Component:
actin cytoskeleton; endoplasmic reticulum-Golgi intermediate compartment; nucleus; plasma membrane
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Molecular Function:
ATP binding; protein kinase activity; protein serine kinase activity; protein serine/threonine kinase activity
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Biological Process:
apoptotic process; intracellular signal transduction; positive regulation of apoptotic process; positive regulation of fibroblast apoptotic process; protein autophosphorylation; protein phosphorylation
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Reference #:
O94768
(UniProtKB)
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Alt. Names/Synonyms: DAP kinase-related apoptosis-inducing protein kinase 2; death-associated protein kinase-related 2; DRAK2; serine/threonine kinase 17b; Serine/threonine-protein kinase 17B; ST17B; STK17B
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Gene Symbols: STK17B
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Molecular weight:
42,344 Da
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Basal Isoelectric point:
5.13
Predict pI for various phosphorylation states
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