DRAK2 Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney. Note: This description may include information from UniProtKB.
Protein type: CAMK group; DAPK family; EC; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of human Ortholog: 2q32.3
Cellular Component:  actin cytoskeleton; endoplasmic reticulum-Golgi intermediate compartment; nucleus; plasma membrane
Molecular Function:  ATP binding; protein kinase activity; protein serine kinase activity; protein serine/threonine kinase activity
Biological Process:  apoptotic process; intracellular signal transduction; positive regulation of apoptotic process; positive regulation of fibroblast apoptotic process; protein autophosphorylation; protein phosphorylation
Reference #:  O94768 (UniProtKB)
Alt. Names/Synonyms: DAP kinase-related apoptosis-inducing protein kinase 2; death-associated protein kinase-related 2; DRAK2; serine/threonine kinase 17b; Serine/threonine-protein kinase 17B; ST17B; STK17B
Gene Symbols: STK17B
Molecular weight: 42,344 Da
Basal Isoelectric point: 5.13  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene