PPP1R15B
Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1. Belongs to the PPP1R15 family. Note: This description may include information from UniProtKB.
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Protein type: Protein phosphatase, regulatory subunit |
Chromosomal Location of mouse Ortholog: 1|1 E4 |
Cellular Component:
endoplasmic reticulum; protein phosphatase type 1 complex
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Molecular Function:
protein phosphatase regulator activity
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Biological Process:
ER overload response; negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation; negative regulation of protein phosphorylation; peptidyl-serine dephosphorylation; positive regulation of phosphoprotein phosphatase activity; regulation of translation; regulation of translational initiation; response to endoplasmic reticulum stress; response to hydrogen peroxide; response to oxidative stress
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Reference #:
Q8BFW3
(UniProtKB)
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Alt. Names/Synonyms: 1810033K10Rik; AI606441; C530022L24Rik; Constitutive repressor of eIF2alpha phosphorylation; CReP; OTTMUSP00000024879; Ppp1r15b; PR15B; Protein phosphatase 1 regulatory subunit 15B; protein phosphatase 1, regulatory (inhibitor) subunit 15b; protein phosphatase 1, regulatory subunit 15B
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Gene Symbols: Ppp1r15b
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Molecular weight:
77,712 Da
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Basal Isoelectric point:
4.92
Predict pI for various phosphorylation states
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