DRAK1 Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas. Note: This description may include information from UniProtKB.
Protein type: CAMK group; DAPK family; EC; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 7p13
Cellular Component:  nuclear speck; nucleus; plasma membrane
Molecular Function:  ATP binding; protein serine/threonine kinase activity
Biological Process:  apoptotic process; intracellular signal transduction; positive regulation of apoptotic process; positive regulation of fibroblast apoptotic process; protein phosphorylation; regulation of reactive oxygen species metabolic process
Reference #:  Q9UEE5 (UniProtKB)
Alt. Names/Synonyms: DAP kinase-related apoptosis-inducing protein kinase 1; death-associated protein kinase-related 1; DRAK1; serine/threonine kinase 17a; serine/threonine kinase 17a (apoptosis-inducing); Serine/threonine-protein kinase 17A; ST17A; STK17A
Gene Symbols: STK17A
Molecular weight: 46,558 Da
Basal Isoelectric point: 5.08  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB