neurogranin Acts as a third messenger substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium. Belongs to the neurogranin family. In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease. Note: This description may include information from UniProtKB.
Protein type: Cell development/differentiation
Cellular Component: 
Molecular Function:  calmodulin binding
Reference #:  P35722 (UniProtKB)
Alt. Names/Synonyms: B-50 immunoreactive C-kinase substrate; BICKS; NEUG; Neurogranin; neurogranin (protein kinase C substrate, RC3); NG; NRGN; P17
Gene Symbols: NRGN
Molecular weight: 7,549 Da
Basal Isoelectric point: 7.72  Predict pI for various phosphorylation states
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neurogranin

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene