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arfaptin 2
Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: GAP; GAP, Rac/Rho; Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 7|7 E3 |
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Cellular Component:
cell cortex; cytoplasm; Golgi apparatus; membrane; nucleolus; ruffle; trans-Golgi network membrane
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Molecular Function:
GTP-dependent protein binding; identical protein binding; membrane curvature sensor activity; phosphatidylinositol-4-phosphate binding; phospholipid binding; protein binding; protein domain specific binding
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Biological Process:
actin cytoskeleton organization; autophagy; intracellular protein transport; mitophagy; protein localization to phagophore assembly site; regulation of Arp2/3 complex-mediated actin nucleation
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Reference #:
Q8K221
(UniProtKB)
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Alt. Names/Synonyms: 2310002N04Rik; ADP-ribosylation factor interacting protein 2; ADP-ribosylation factor-interacting protein 2; Arfaptin 2; Arfaptin-2; Arfip2; ARFP2; OTTMUSP00000031019; OTTMUSP00000031020; partner of RAC1; POR; Por1
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Gene Symbols: Arfip2
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Molecular weight:
37,773 Da
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Basal Isoelectric point:
5.61
Predict pI for various phosphorylation states
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