arfaptin 2 Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho; Motility/polarity/chemotaxis
Chromosomal Location of mouse Ortholog: 7|7 E3
Cellular Component:  cell cortex; cytoplasm; Golgi apparatus; membrane; nucleolus; ruffle; trans-Golgi network membrane
Molecular Function:  GTP-dependent protein binding; identical protein binding; membrane curvature sensor activity; phosphatidylinositol-4-phosphate binding; phospholipid binding; protein binding; protein domain specific binding
Biological Process:  actin cytoskeleton organization; autophagy; intracellular protein transport; mitophagy; protein localization to phagophore assembly site; regulation of Arp2/3 complex-mediated actin nucleation
Reference #:  Q8K221 (UniProtKB)
Alt. Names/Synonyms: 2310002N04Rik; ADP-ribosylation factor interacting protein 2; ADP-ribosylation factor-interacting protein 2; Arfaptin 2; Arfaptin-2; Arfip2; ARFP2; OTTMUSP00000031019; OTTMUSP00000031020; partner of RAC1; POR; Por1
Gene Symbols: Arfip2
Molecular weight: 37,773 Da
Basal Isoelectric point: 5.61  Predict pI for various phosphorylation states
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arfaptin 2

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein