arfaptin 2 Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component:  cell cortex; cytoplasm; cytosol; plasma membrane; ruffle; trans-Golgi network membrane
Molecular Function:  GTP binding; GTP-dependent protein binding; identical protein binding; phosphatidylinositol-4-phosphate binding; protein binding; protein domain specific binding; Rac GTPase binding
Biological Process:  actin cytoskeleton organization; lamellipodium assembly; ruffle organization; small GTPase mediated signal transduction
Reference #:  P53365 (UniProtKB)
Alt. Names/Synonyms: ADP-ribosylation factor interacting protein 2; ADP-ribosylation factor-interacting protein 2; arfaptin 2; Arfaptin-2; ARFIP2; ARFP2; Partner of RAC1; partner of RAC1 (arfaptin 2); POR1; Protein POR1
Gene Symbols: ARFIP2
Molecular weight: 37,856 Da
Basal Isoelectric point: 5.72  Predict pI for various phosphorylation states
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arfaptin 2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein