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ZDHHC22
Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane. Might also mediate palmitoylation of CNN3. Belongs to the DHHC palmitoyltransferase family. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.3.1.225; Membrane protein, integral; Membrane protein, multi-pass; Transferase |
| Chromosomal Location of human Ortholog: 14q24.3 |
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Cellular Component:
endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; plasma membrane
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Molecular Function:
protein binding; protein-cysteine S-palmitoyltransferase activity
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Biological Process:
peptidyl-L-cysteine S-palmitoylation; protein localization to plasma membrane; protein palmitoylation; protein targeting to membrane
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Reference #:
Q8N966
(UniProtKB)
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Alt. Names/Synonyms: C14orf59; DHHC-22; Palmitoyltransferase ZDHHC22; Putative palmitoyltransferase ZDHHC22; ZDH22; ZDHHC22; Zinc finger DHHC domain-containing protein 22; zinc finger DHHC-type containing 22; zinc finger DHHC-type palmitoyltransferase 22; zinc finger, DHHC domain containing 22; zinc finger, DHHC-type containing 22
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Gene Symbols: ZDHHC22
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Molecular weight:
29,100 Da
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Basal Isoelectric point:
9.5
Predict pI for various phosphorylation states
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