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CTRC
Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity. Belongs to the peptidase S1 family. Elastase subfamily. Pancreas. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.4.21.2; Protease |
| Chromosomal Location of human Ortholog: 1p36.21 |
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Cellular Component:
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Molecular Function:
peptidase activity; protein binding; serine-type endopeptidase activity
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Biological Process:
intracellular calcium ion homeostasis; proteolysis
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Disease: Pancreatitis, Hereditary
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Reference #:
Q99895
(UniProtKB)
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Alt. Names/Synonyms: Caldecrin; chymotrypsin C; chymotrypsin C (caldecrin); Chymotrypsin-C; CLCR; CTRC; ELA4; elastase 4; elastase IV; serum calcium decreasing factor
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Gene Symbols: CTRC
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Molecular weight:
29,484 Da
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Basal Isoelectric point:
7.54
Predict pI for various phosphorylation states
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