DLX3 Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis. Belongs to the distal-less homeobox family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 11 D|11 59.01 cM
Cellular Component:  nucleus
Molecular Function:  chromatin binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; RNA polymerase II proximal promoter sequence-specific DNA binding; sequence-specific DNA binding
Biological Process:  blood vessel development; cell differentiation; epithelial cell differentiation; multicellular organism development; odontoblast differentiation; odontogenesis of dentin-containing tooth; placenta development; regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated
Reference #:  Q64205 (UniProtKB)
Alt. Names/Synonyms: AV237891; DII C; distal-less homeobox 3; Dlx-; Dlx-3; Dlx3; Homeobox protein DLX-3; OTTMUSP00000001527
Gene Symbols: Dlx3
Molecular weight: 31,791 Da
Basal Isoelectric point: 8.98  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene