SLC27A3
Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. Does not exhibit fatty acid transport activity. Belongs to the ATP-dependent AMP-binding enzyme family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: EC 6.2.1.-; Ligase; Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial |
Chromosomal Location of mouse Ortholog: 3|3 F1 |
Cellular Component:
endoplasmic reticulum; membrane; mitochondrial matrix; mitochondrion
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Molecular Function:
arachidonate-CoA ligase activity; ATP binding; fatty-acyl-CoA synthase activity; ligase activity; long-chain fatty acid transporter activity; long-chain fatty acid-CoA ligase activity; nucleotide binding; very long-chain fatty acid-CoA ligase activity
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Biological Process:
acyl-CoA metabolic process; fatty acid metabolic process; fatty acid transport; lipid metabolic process; lipid transport; long-chain fatty acid metabolic process
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Reference #:
O88561
(UniProtKB)
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Alt. Names/Synonyms: Acsvl3; Arachidonate--CoA ligase; FAT; FATP-3; Fatp3; Fatty acid transport protein 3; Long-chain fatty acid transport protein 3; mFLJ00207 protein; S27A3; Slc27a3; solute carrier family 27 (fatty acid transporter), member 3; Solute carrier family 27 member 3; very long-chain acyl-CoA synthetase homolog 3; Vlcs-3
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Gene Symbols: Slc27a3
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Molecular weight:
72,965 Da
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Basal Isoelectric point:
7.59
Predict pI for various phosphorylation states
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