PAFAH1B3 Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain. Belongs to the 'GDSL' lipolytic enzyme family. Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.1.47; Lipase; Lipid Metabolism - ether lipid
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component:  cytosol
Molecular Function:  1-alkyl-2-acetylglycerophosphocholine esterase activity; identical protein binding; protein binding; protein heterodimerization activity
Biological Process:  lipid catabolic process; lipid metabolic process; nervous system development; spermatogenesis
Reference #:  Q15102 (UniProtKB)
Alt. Names/Synonyms: FLJ44990; PA1B3; PAF acetylhydrolase 29 kDa subunit; PAF-AH 29 kDa subunit; PAF-AH subunit gamma; PAF-AH1b alpha 1 subunit; PAFAH subunit gamma; PAFAH1B3; PAFAHG; platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa); Platelet-activating factor acetylhydrolase IB subunit gamma; platelet-activating factor acetylhydrolase, isoform Ib, subunit 3 (29kDa)
Gene Symbols: PAFAH1B3
Molecular weight: 25,734 Da
Basal Isoelectric point: 6.33  Predict pI for various phosphorylation states
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PAFAH1B3

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene