BVR Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily. Liver. Note: This description may include information from UniProtKB.
Protein type: ATYPICAL group; BLVRA family; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 1.3.1.24; Kinase, protein; Oxidoreductase; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 2 F1|2 61.76 cM
Cellular Component:  cytoplasm; cytosol
Molecular Function:  biliverdin reductase activity; metal ion binding; nucleotide binding; oxidoreductase activity; zinc ion binding
Biological Process:  heme catabolic process; oxidation-reduction process
Reference #:  Q9CY64 (UniProtKB)
Alt. Names/Synonyms: 0610006A11Rik; 2500001N03Rik; BIEA; Biliverdin reductase A; Biliverdin-IX alpha-reductase; Blvr; Blvra; BVR; BVR A; OTTMUSP00000017108
Gene Symbols: Blvra
Molecular weight: 33,525 Da
Basal Isoelectric point: 6.53  Predict pI for various phosphorylation states
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BVR

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene