TUBA1B
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
Protein type: Cytoskeletal; Motility/polarity/chemotaxis |
Chromosomal Location of mouse Ortholog: 15|15 F1 |
Cellular Component:
cytoplasm; cytoplasmic microtubule; cytoskeleton; cytosol; membrane raft; microtubule; microtubule cytoskeleton
|
Molecular Function:
double-stranded RNA binding; GTP binding; GTPase activity; hydrolase activity; metal ion binding; nucleotide binding; protein binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding
|
Biological Process:
cellular response to interleukin-4; microtubule cytoskeleton organization; microtubule-based process; mitotic cell cycle
|
Reference #:
P05213
(UniProtKB)
|
Alt. Names/Synonyms: Alpha-tubulin 2; Alpha-tubulin isotype M-alpha-2; Detyrosinated tubulin alpha-1B chain; MGC102558; MGC117866; MGC118411; OTTMUSP00000018538; TBA1B; Tuba; Tuba1b; Tuba2; Tubulin alpha-1B chain; Tubulin alpha-2 chain; tubulin, alpha 1B; tubulin, alpha 2
|
Gene Symbols: Tuba1b
|
Molecular weight:
50,152 Da
|
Basal Isoelectric point:
4.94
Predict pI for various phosphorylation states
|
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
|