TUBA1B Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 15|15 F1
Cellular Component:  cytoplasm; cytoplasmic microtubule; cytoskeleton; microtubule; microtubule cytoskeleton
Molecular Function:  double-stranded RNA binding; GTP binding; GTPase activity; nucleotide binding; protein binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding
Biological Process:  cellular response to interleukin-4; microtubule cytoskeleton organization; microtubule-based process; mitotic cell cycle
Reference #:  P05213 (UniProtKB)
Alt. Names/Synonyms: Alpha-tubulin 2; Alpha-tubulin isotype M-alpha-2; Detyrosinated tubulin alpha-1B chain; MGC102558; MGC117866; MGC118411; OTTMUSP00000018538; TBA1B; Tuba; Tuba1b; Tuba2; Tubulin alpha-1B chain; Tubulin alpha-2 chain; tubulin, alpha 1B; tubulin, alpha 2
Gene Symbols: Tuba1b
Molecular weight: 50,152 Da
Basal Isoelectric point: 4.94  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below

TUBA1B

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene