Claudin-3 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Belongs to the claudin family. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 5 G2|5 74.93 cM
Cellular Component:  apicolateral plasma membrane; bicellular tight junction; cell junction; cytoplasm; integral component of membrane; lateral plasma membrane; membrane; plasma membrane
Molecular Function:  identical protein binding; protein binding; structural molecule activity
Biological Process:  bicellular tight junction assembly; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; epithelial cell morphogenesis; protein heterooligomerization; protein homooligomerization
Reference #:  Q9Z0G9 (UniProtKB)
Alt. Names/Synonyms: AI182374; claudin 3; Claudin-3; claudin3; CLD3; Cldn3; Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2; Cpet; Cpetr2; mRVP1; OTTMUSP00000025806
Gene Symbols: Cldn3
Molecular weight: 23,285 Da
Basal Isoelectric point: 8.02  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene