KDELR1 Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L. Belongs to the ERD2 family. Note: This description may include information from UniProtKB.
Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 7|7 B3
Cellular Component:  cis-Golgi network; cytoplasmic vesicle; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; Golgi membrane; integral component of membrane; membrane
Molecular Function:  ER retention sequence binding; KDEL sequence binding
Biological Process:  ER to Golgi vesicle-mediated transport; protein retention in ER lumen; protein transport; retrograde vesicle-mediated transport, Golgi to ER; T cell apoptotic process; T cell cytokine production; T cell differentiation; vesicle-mediated transport
Reference #:  Q99JH8 (UniProtKB)
Alt. Names/Synonyms: 8030486F04Rik; AW215843; ER lumen protein retaining receptor 1; ER lumen protein-retaining receptor 1; Erd2.1; ERD21; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; Kdelr1; OTTMUSP00000025260
Gene Symbols: Kdelr1
Molecular weight: 24,560 Da
Basal Isoelectric point: 8.8  Predict pI for various phosphorylation states
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KDELR1

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene