KDELR1 Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum. Belongs to the ERD2 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 7|7 B3
Cellular Component:  cis-Golgi network; cytoplasmic vesicle; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; Golgi membrane; integral component of membrane; membrane
Molecular Function:  ER retention sequence binding; KDEL sequence binding
Biological Process:  ER to Golgi vesicle-mediated transport; protein retention in ER lumen; protein transport; retrograde vesicle-mediated transport, Golgi to ER; T cell apoptotic process; T cell cytokine production; T cell differentiation; vesicle-mediated transport
Reference #:  Q99JH8 (UniProtKB)
Alt. Names/Synonyms: 8030486F04Rik; AW215843; ER lumen protein retaining receptor 1; ER lumen protein-retaining receptor 1; Erd2.1; ERD21; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; Kdelr1; OTTMUSP00000025260
Gene Symbols: Kdelr1
Molecular weight: 24,560 Da
Basal Isoelectric point: 8.8  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene