|
DATF1
Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Required for early embryonic stem cell development. Isoform 2: Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes. Ubiquitous. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Transcription factor |
| Chromosomal Location of mouse Ortholog: 2|2 H4 |
|
Cellular Component:
cytoplasm; cytoskeleton; nucleoplasm; nucleus
|
|
Molecular Function:
metal ion binding
|
|
Biological Process:
apoptotic process; apoptotic signaling pathway; DNA-templated transcription
|
|
Reference #:
Q8C9B9
(UniProtKB)
|
|
Alt. Names/Synonyms: 6720461J16Rik; C130092D22Rik; C530043I07; D130048F08Rik; Datf; DATF-1; Datf1; death inducer-obliterator 1; death inducer-obliterator-2; death inducer-obliterator-3; Death-associated transcription factor 1; Death-inducer obliterator 1; dido; Dido1; Dido2; Dido3; DIO; DIO-1; Dio1; mKIAA0333; OTTMUSP00000017582; OTTMUSP00000017583; OTTMUSP00000017584; OTTMUSP00000017585; OTTMUSP00000017586
|
|
Gene Symbols: Dido1
|
|
Molecular weight:
247,176 Da
|
|
Basal Isoelectric point:
8.11
Predict pI for various phosphorylation states
|
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
|
