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DATF1
Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Required for early embryonic stem cell development. Isoform 2: Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes. Ubiquitous. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Transcription factor |
| Chromosomal Location of Human Ortholog: 2|2 H4 |
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Cellular Component:
cytoplasm; cytoskeleton; nucleus
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Molecular Function:
metal ion binding
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Biological Process:
apoptotic process; apoptotic signaling pathway; transcription, DNA-templated
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Reference #:
Q8C9B9
(UniProtKB)
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Alt. Names/Synonyms: 6720461J16Rik; C130092D22Rik; C530043I07; D130048F08Rik; Datf; DATF-1; Datf1; death inducer-obliterator 1; death inducer-obliterator-2; death inducer-obliterator-3; Death-associated transcription factor 1; Death-inducer obliterator 1; dido; Dido1; Dido2; Dido3; DIO; DIO-1; Dio1; mKIAA0333; OTTMUSP00000017582; OTTMUSP00000017583; OTTMUSP00000017584; OTTMUSP00000017585; OTTMUSP00000017586
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Gene Symbols: Dido1
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Molecular weight:
247,176 Da
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Basal Isoelectric point:
8.11
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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