|
NDUFA10
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA10 subunit family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: EC 1.6.5.3; EC 1.6.99.3; Energy Metabolism - oxidative phosphorylation; Mitochondrial; Oxidoreductase |
| Chromosomal Location of human Ortholog: 2q37.3 |
|
Cellular Component:
mitochondrial inner membrane; mitochondrial matrix; mitochondrial respiratory chain complex I; mitochondrion
|
|
Molecular Function:
NADH dehydrogenase (ubiquinone) activity
|
|
Biological Process:
mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly
|
|
Disease: Mitochondrial Complex I Deficiency, Nuclear Type 22
|
|
Reference #:
O95299
(UniProtKB)
|
|
Alt. Names/Synonyms: CI-42k; CI-42kD; complex I 42kDa subunit; Complex I-42kD; FLJ21923; MC1DN22; MGC5103; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; NADH-ubiquinone oxidoreductase 42 kDa subunit; NADH:ubiquinone oxidoreductase subunit A10; NDUAA; NDUFA10
|
|
Gene Symbols: NDUFA10
|
|
Molecular weight:
40,751 Da
|
|
Basal Isoelectric point:
8.67
Predict pI for various phosphorylation states
|
