PKACG Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript. Note: This description may include information from UniProtKB.
Protein type: AGC group; EC; Kinase, protein; PKA family; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 9q21.11
Cellular Component:  ciliary base; cytosol; intercellular bridge; nucleoplasm
Molecular Function:  ATP binding; cAMP-dependent protein kinase activity
Biological Process:  activation of protein kinase A activity; blood coagulation; cellular response to glucagon stimulus; high-density lipoprotein particle assembly; male gonad development; protein phosphorylation; renal water homeostasis; spermatogenesis; stimulatory C-type lectin receptor signaling pathway
Disease: Mental Retardation, Autosomal Dominant 31
Reference #:  P22612 (UniProtKB)
Alt. Names/Synonyms: BDPLT19; cAMP-dependent protein kinase catalytic subunit gamma; KAPCG; KAPG; PKA C-gamma; PKACg; PRKACG; protein kinase cAMP-activated catalytic subunit gamma; protein kinase, cAMP-dependent, catalytic, gamma; protein kinase, cAMP-dependent, gamma catalytic subunit; serine(threonine) protein kinase
Gene Symbols: PRKACG
Molecular weight: 40,434 Da
Basal Isoelectric point: 8.7  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics  |  AMPK Signaling  |  GPCR Signaling to MAPKs  |  Growth And Differentiation Control by MAPKs  |  Hedgehog Signaling  |  Inhibition of Apoptosis  |  Insulin Receptor Signaling  |  Microtubule Dynamics  |  Mitochondrial Control of Apoptosis  |  NF-kB Signaling  |  Parkinson's Disease
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene