neurabin 1 Binds to actin filaments (F-actin) and shows cross- linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1- alpha activity. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Protein phosphatase, regulatory subunit
Chromosomal Location of Human Ortholog: 7q21.3
Cellular Component:  actin cytoskeleton; cell junction; cell soma; cortical actin cytoskeleton; cytoplasm; cytosol; dendrite; dendritic spine neck; filopodium; neuromuscular junction; postsynaptic density
Molecular Function:  actin filament binding; GTPase binding; ion channel binding; protein binding; protein C-terminus binding; protein domain specific binding; protein homodimerization activity; protein kinase binding; protein phosphatase 1 binding
Biological Process:  actin filament organization; aging; calcium-mediated signaling; excitatory postsynaptic potential; negative regulation of long-term synaptic potentiation; negative regulation of spontaneous neurotransmitter secretion; negative regulation of stress fiber formation; neuron projection development; positive regulation of long term synaptic depression; positive regulation of protein kinase activity; regulation of actin filament polymerization; regulation of filopodium formation; regulation of synapse assembly; regulation of synapse structural plasticity
Reference #:  Q9ULJ8 (UniProtKB)
Alt. Names/Synonyms: FLJ20068; KIAA1222; NEB1; Neurabin-1; Neurabin-I; Neural tissue-specific F-actin-binding protein I; NRB1; NRBI; PPP1R9A; Protein phosphatase 1 regulatory subunit 9A; protein phosphatase 1, regulatory (inhibitor) subunit 9A
Gene Symbols: PPP1R9A
Molecular weight: 123,342 Da
Basal Isoelectric point: 5.01  Predict pI for various phosphorylation states
Select Structure to View Below

neurabin 1

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein