PKN3 Contributes to invasiveness in malignant prostate cancer. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues. Note: This description may include information from UniProtKB.
Protein type: AGC group; EC; Kinase, protein; PKN family; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of human Ortholog: 9q34.11
Cellular Component:  cytosol; Golgi apparatus; nucleus; perinuclear region of cytoplasm
Molecular Function:  ATP binding; calcium-dependent protein kinase C activity; protein binding; protein kinase activity; protein serine kinase activity; protein serine/threonine kinase activity; small GTPase binding
Biological Process:  epithelial cell migration; intracellular signal transduction; peptidyl-serine phosphorylation; protein phosphorylation; signal transduction
Reference #:  Q6P5Z2 (UniProtKB)
Alt. Names/Synonyms: PKN3; PKNBETA; protein kinase N3; Protein kinase PKN-beta; Protein-kinase C-related kinase 3; RP11-545E17.1; Serine/threonine-protein kinase N3; UTDP4-1
Gene Symbols: PKN3
Molecular weight: 99,421 Da
Basal Isoelectric point: 8.77  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene