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RhoE
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Belongs to the small GTPase superfamily. Rho family. Ubiquitous. Note: This description may include information from UniProtKB.
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| Protein type: G protein; G protein, monomeric; G protein, monomeric, Rho; Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 2|2 C1.1 |
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Cellular Component:
cell cortex; cell division site; cytoplasm; Golgi apparatus; intracellular membrane-bounded organelle; membrane
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Molecular Function:
GTP binding; GTPase activity; nucleotide binding; protein binding; protein kinase binding
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Biological Process:
actin filament bundle assembly; actin filament organization; establishment or maintenance of actin cytoskeleton polarity; regulation of actin cytoskeleton organization; regulation of cell migration; regulation of cell shape; Rho protein signal transduction; small GTPase mediated signal transduction
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Reference #:
P61588
(UniProtKB)
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Alt. Names/Synonyms: 2610017M01Rik; AI661404; Arhe; OTTMUSP00000013299; ras homolog gene family, member E; Rho family GTPase 3; Rho-related GTP-binding protein RhoE; Rhoe; Rnd3
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Gene Symbols: Rnd3
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Molecular weight:
27,368 Da
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Basal Isoelectric point:
8.78
Predict pI for various phosphorylation states
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CST Pathways:
Actin Dynamics
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Microtubule Dynamics
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