RhoE Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. Belongs to the small GTPase superfamily. Rho family. Ubiquitous. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rho; Motility/polarity/chemotaxis
Chromosomal Location of mouse Ortholog: 2|2 C1.1
Cellular Component:  cell cortex; cell division site; cytoplasm; Golgi apparatus; intracellular membrane-bounded organelle; membrane
Molecular Function:  GTP binding; GTPase activity; nucleotide binding; protein binding; protein kinase binding
Biological Process:  actin filament bundle assembly; actin filament organization; establishment or maintenance of actin cytoskeleton polarity; regulation of actin cytoskeleton organization; regulation of cell migration; regulation of cell shape; Rho protein signal transduction; small GTPase mediated signal transduction
Reference #:  P61588 (UniProtKB)
Alt. Names/Synonyms: 2610017M01Rik; AI661404; Arhe; OTTMUSP00000013299; ras homolog gene family, member E; Rho family GTPase 3; Rho-related GTP-binding protein RhoE; Rhoe; Rnd3
Gene Symbols: Rnd3
Molecular weight: 27,368 Da
Basal Isoelectric point: 8.78  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics  |  Microtubule Dynamics
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene