amphiphysin May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton. Neurons, certain endocrine cell types and spermatocytes. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 7p14.1
Cellular Component:  actin cytoskeleton; cell junction; cytosol; leading edge membrane; synaptic vesicle membrane
Molecular Function:  phospholipid binding; protein binding
Biological Process:  chemical synaptic transmission; endocytosis; membrane organization
Reference #:  P49418 (UniProtKB)
Alt. Names/Synonyms: AMPH; AMPH1; Amphiphysin; amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen); Stiff-Man syndrome with breast cancer 128kDa autoantigen
Gene Symbols: AMPH
Molecular weight: 76,257 Da
Basal Isoelectric point: 4.58  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein