MP20 Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis. Belongs to the PMP-22/EMP/MP20 family. Eye lens specific. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: 
Molecular Function:  structural constituent of eye lens
Biological Process:  lens development in camera-type eye
Reference #:  P20274 (UniProtKB)
Alt. Names/Synonyms: Lens fiber membrane intrinsic protein; LIM2; LMIP; MP18; MP19; MP20; MP21; MP23
Gene Symbols: LIM2
Molecular weight: 19,684 Da
Basal Isoelectric point: 9.64  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein